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antibiotics and UC

Question:

– Hide quoted text — Show quoted text – With the hope that H. pylori is the cause of UC  I did 3 weeks of antibiotics.  The results were amazing! Within 4 days I had relief from most major symptoms.  No pain, no mucus in stools, my diarrhea disapeared, sleep all night, no bowel movements till hours (1-2) after a meal. I thought this was a cure! I could eat pizza and drink beer with no problems! One week after beginning off the antibiotics UC has returned! Has anyone else had temporary relief with antibiotics? Please post or email thanks, John Dey Las Vegas Nevada I heard these antibiotics for H-pylori sould be taken for 9 months. 1 friend was put on it for only a short time also here in California. Stan

WHAT ANTIBIOTIC AND WHAT DOSE!!!!! claire

Response:

With the hope that H. pylori is the cause of UC  I did 3 weeks of antibiotics.  The results were amazing! (snipped) One week after beginning off the antibiotics UC has returned! Has anyone else had temporary relief with antibiotics? Before my resection, I had significant relief from my CD symptoms whenever I had a course of tetracycline (for some non-CD reason). I reported this to my GI doc, who acknowledged that it sometimes works that way, that nobody knows why it does, but "you can’t take tetracycline forever."

I am currently taking doxycycline for interstitial cystitis, but my gastro. and I thought it would be interesting to see if it also helped my bowel inflammation.  Well, I had the same results as John (above) – the first week, I was a lot better, then I had a week or so of being about the same as before, but now I’m on my 4th week and I think it’s improving again.  I’m not sure how long I’ll be on the antibiotic, but my doc. didn’t seem to think a few months would hurt.  Of course, we discussed the possibility of my developing a bacteria that is antibiotic-resistant (which seems to be the main risk to taking doxycycline), but I decided to try it for a while anyway. (BTW, it hasn’t helped my interstitial cystitis at all, but that may take longer). I think that there is a good possibility that there is some bacterial component involved in IBD, coupled with a genetic predisposition in some people to react more strongly to the bacteria.  (Have any of you been tested for the HLA-B27 genetic marker?)  So, antibiotics might help in getting the disease somewhat under control, but I don’t think it’s the whole story.  I just hope to get the diahrrea controlled better.

Response:

- Hide quoted text — Show quoted text – Wayne, Taking antibiotics certainly does kill off many of your intestinal flora. However, various antibiotics are specific for different classes of bacteria, so that one antibiotic cannot kill off all the different species.  However, lowering the population of one species may allow another to take over.  Thus the flora mix can be changed. In addition, it is entirely possible that the antibiotic did not kill off even all of the species it is specific for–antibiotic-resistant bacteria.  In this case, after stopping the antibiotic, the bacteria will grow back because not all of them were killed.  Even without antibiotic-resistant species, not all of a particular antibiotic-sensitive species might be killed, and once the antibiotic is removed, they will grow back. There is some evidence to associate ‘pathogenic’ bacteria with ulcerative colitis.  There has been some apparent success in ‘curing’ UC by killing off all (or as many as possible) of the intestinal flora and repopulating with a mix of non-pathogenic bacteria.  Controlled trials have not yet been run on this procedure and the population of patients treated is small.  Therefore any data is not as hard as one might like.  However, I think it is a promising treatment. Bill Bill Lazar Paetzold Square Bass Recorders 1377 Bluebird Ct. Sunnyvale, CA 94087 (408)737-8228 (phone & Fax)

Think of your intestinal tract as a battleground. The enemy is Candida and other "bad bacteria". They have proliferated and have taken over the G.I. tract. This in turn is causing problems with your health. You as the leader send in a platoon of good guys (acidophilus). The platoon becomes outnumbered. They put up a courageous fight and manage to kill off some of the enemy but become overpowered and lose the battle.         Learning from your mistake, you send in several batallions consisting of many "good bacteria", one after the other. The enemy is bombarded and has no time to regroup. They are wiped out and the battle has been won.         Now the good bacteria can establish itself and colonize the G.I. tract. If any "unfriendly bacteria" happen to find their way back into the tract, they are, so to speak, "Blasted out of the water".

Response:

Wayne, Taking antibiotics certainly does kill off many of your intestinal flora. However, various antibiotics are specific for different classes of bacteria, so that one antibiotic cannot kill off all the different species.  However, lowering the population of one species may allow another to take over.  Thus the flora mix can be changed.   In addition, it is entirely possible that the antibiotic did not kill off even all of the species it is specific for–antibiotic-resistant bacteria.  In this case, after stopping the antibiotic, the bacteria will grow back because not all of them were killed.  Even without antibiotic-resistant species, not all of a particular antibiotic-sensitive species might be killed, and once the antibiotic is removed, they will grow back.   There is some evidence to associate ‘pathogenic’ bacteria with ulcerative colitis.  There has been some apparent success in ‘curing’ UC by killing off all (or as many as possible) of the intestinal flora and repopulating with a mix of non-pathogenic bacteria.  Controlled trials have not yet been run on this procedure and the population of patients treated is small.  Therefore any data is not as hard as one might like.  However, I think it is a promising treatment. Bill Bill Lazar Paetzold Square Bass Recorders 1377 Bluebird Ct. Sunnyvale, CA 94087 (408)737-8228 (phone & Fax)

Response:

- Hide quoted text — Show quoted text -With the hope that H. pylori is the cause of UC  I did 3 weeks of antibiotics.  The results were amazing! Within 4 days I had relief from most major symptoms.  No pain, no mucus in stools, my diarrhea disapeared, sleep all night, no bowel movements till hours (1-2) after a meal. I thought this was a cure! I could eat pizza and drink beer with no problems! One week after beginning off the antibiotics UC has returned! Has anyone else had temporary relief with antibiotics? Please post or email thanks, John Dey Las Vegas Nevada

I heard these antibiotics for H-pylori sould be taken for 9 months. 1 friend was put on it for only a short time also here in California. Stan

Response:

It is not enough to kill off the bad bacteria.  If you do not replace them with good ones, the bad ones will grow back.  You not only need Acidophilus and Bifido, but a non-pathogenic strain of E. coli. Bill Bill Lazar Paetzold Square Bass Recorders 1377 Bluebird Ct. Sunnyvale, CA 94087 (408)737-8228 (phone & Fax)

Response:

It is not enough to kill off the bad bacteria.  If you do not replace them with good ones, the bad ones will grow back.  You not only need Acidophilus and Bifido, but a non-pathogenic strain of E. coli.

I’m pretty skeptical about this good bacteria/bad bacteria talk. (This is not a flame of Bill Lazar.) Has anyone seen any actual research on this topic? How does a child come to have the right assortment of good bacteria in his gut in the first place? Hundreds of millions of people take oral antibiotics every year, presumably killing off all their good and bad gut bacteria. Almost all of them recover normal gut function after a short (or no) period of diarrhea, etc. without taking Acidophilus etc. concoctions. How does that happen? If we IBDers can’t sustain the right assortment of good bacteria in our guts, maybe our guts are essentially inhospitable to those bacteria, and no amount of yogurt, etc. will make any difference for us. —

Response:

With the hope that H. pylori is the cause of UC  I did 3 weeks of antibiotics.  The results were amazing! Within 4 days I had relief from most major symptoms.  No pain, no mucus in stools, my diarrhea disapeared, sleep all night, no bowel movements till hours (1-2) after a meal. I thought this was a cure! I could eat pizza and drink beer with no problems! One week after beginning off the antibiotics UC has returned!

Was this treatment monitored by your Dr ?  Perhaps you needed more than 3 weeks. Perhaps a different antibiotic was needed ? Which antibiotic were you using by the way ? AS. – Hide quoted text — Show quoted text -Has anyone else had temporary relief with antibiotics? Please post or email thanks, John Dey Las Vegas Nevada

Response:

- Hide quoted text — Show quoted text – With the hope that H. pylori is the cause of UC  I did 3 weeks of antibiotics.  The results were amazing! Within 4 days I had relief from most major symptoms.  No pain, no mucus in stools, my diarrhea disapeared, sleep all night, no bowel movements till hours (1-2) after a meal. I thought this was a cure! I could eat pizza and drink beer with no problems! One week after beginning off the antibiotics UC has returned! Has anyone else had temporary relief with antibiotics? Please post or email thanks, John Dey Las Vegas NevadaHave you looked into acidophilus and bifidus to rebuild you intestinal

or search the net. I’ve "Been there, done it , got the T-shirt". E.Young

  Acidoph.doc

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Response:

With the hope that H. pylori is the cause of UC  I did 3 weeks of antibiotics.  The results were amazing! Within 4 days I had relief from most major symptoms.  No pain, no mucus in stools, my diarrhea disapeared, sleep all night, no bowel movements till hours (1-2) after a meal. I thought this was a cure! I could eat pizza and drink beer with no problems! One week after beginning off the antibiotics UC has returned! Has anyone else had temporary relief with antibiotics?

Before my resection, I had significant relief from my CD symptoms whenever I had a course of tetracycline (for some non-CD reason). I reported this to my GI doc, who acknowledged that it sometimes works that way, that nobody knows why it does, but "you can’t take tetracycline forever." I was recently diagnosed with a mild (so far) case of rosacea. First therapy is metronidazole gel applied to the skin topically. If that doesn’t work, the second therapy is a weak dose of tetracycline by mouth, forever. I asked my GI doc if he had any objection to the skin doc prescribing tetracycline, if it came to that. The GI doc said no. Now I’m ambivalent about the rosacea. On the one hand, I don’t want it to get worse. On the other hand, I’d like to get hold of some tetracycline again. —

Response:

With the hope that H. pylori is the cause of UC  I did 3 weeks of antibiotics.  The results were amazing! Within 4 days I had relief from most major symptoms.  No pain, no mucus in stools, my diarrhea disapeared, sleep all night, no bowel movements till hours (1-2) after a meal. I thought this was a cure! I could eat pizza and drink beer with no problems! One week after beginning off the antibiotics UC has returned! Has anyone else had temporary relief with antibiotics? Please post or email thanks, John Dey Las Vegas Nevada

Response:

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